Searchable abstracts of presentations at key conferences in endocrinology

ea0075t06 | Thyroid | EYES2021

Ectopic Cushing’s syndrome due to advanced medullary thyroid cancer: a case report

Corsello Andrea , Ramunno Vittoria , Paragliola Rosa Maria , Pacini Giovanni , De Crea Carmela , Raffaelli Marco , Locantore Pietro

Background: Cushing’s syndrome (CS) in medullary thyroid cancer (MTC) is rare with less than 60 cases reported. Less than 1% of MTC develop ectopic ACTH-dependent CS and this correlated with metastasis at diagnosis and poor prognosis.Case presentation: A 32-year-old male was referred to our department for suspected CS. Initial evaluation showed hypokalemia(2.4 mmol/l) and severe ACTH-dependent CS (Cortisol h8:678ng/ml; ACTH:249pg/ml; urinary free co...